Many of the traditional D&D and Pathfinder gods are worshipped in my world, although several home-brew deities have a following as well. However, rather than worshipping individual deities, most people in the world venerate their local pantheon, and recognize the deities of other regions as well. Most gods have their own priests and temples, but some priests might represent a whole pantheon of deities - The Green is a good example of that.
The Three Sisters
The three female over-deities, triplets whose origins are unknown, are all True Neutral. They are grand and well known to high priests across the world - however, they are distant. They do not have churches or priesthoods and do not grant spells to mortals, nor do they recognize mortal prayers, but are believed to be the patrons and creators of deities and similar powers (past and Present). They are believed to be served by every deity, power or psychopomp, who can grant any of their domains – regardless of alignment. For Example
There are many deities from 'traditional' pantheons that I like and incorporate in my games. Some, however, need tweaking to fit in with the game world.
Wee Jas - I have always liked Wee-Jas, and thought that she was one of the more original deities from the D&D pantheon. She started off as a Lawful Neutral deity, changed to having Evil tendencies, but, with 5e, seems to have returned to her earlier philosophies. I have three separate 'churches' spread around my campaign world: One with strongly LE philosophies, that is a hangover from earlier time, and two others that are more palatable in the 'modern' world.
Official Deities - My take on deities from the 3.5 and PF pantheons.
They aren't completely home-brewed :) Some contain deities from the D&D 3.5 rules, some include deities from the pathfinder rules, a few of them are home-brew deities, and some are just different presentations of something that already exists in the rules. However, I feel they give my worlds a slightly different feel, and might make players think about their character background and personality a bit more. All grist to the mill of role-playing.
The following are a group of bespoke deities and immortals, who have appeared in my games. Most are very minor deities, but they give the world a bit of extra flavour.
Some of these deities are associated with The Paths of the Dead - an RP description of that refers to one aspect of the Plane of Shadow. I borrowed this concept from a game that I played in many years ago when the character, who evolved into Gasgano, found a 'Book of the Dead' which allowed access to grey, colourless, passageways - filled with undead - that allowed fast travel around the world. I used the concept, slightly modified, when I was building death and resurrection systems for Neverwinter Nights persistent worlds, and have used the same concept here.
Demigods are true gods, capable of granting a selection of domains, and offer the full range of divine spells to their priests. They follow all the standard Pathfinder rules for deities.
Nature spirits are strange things, they aren't really gods, in the sense that they need worshippers and priests, but some of them can grant divine spells to their 'priests'. Examples of Nature Spirits, that can be treated as deities, are listed below.
This does not conform with either the 3.5 or Pathfinder rules, but reverts (in some ways) to some of the earlier definitions. In some earlier versions of the game, lower level deities could not grant high level spells to their priests, Demi-Gods (for example) were restricted to granting 5th level spells and below. These Quasi-deities echo that by only being able to grant spells from the (standard) Adept spell list, and only have access to two domains.
They are well suited for NPCs and would also suit PCs who are not expected to reach high levels in their divine casting class. Some players might find the mix of spells, many of which are not available to conventional clerics, interesting.